How Can we Study Cardiopulmonary Resuscitation and Cardiac Arrest in Animals: a Review
| Autor: | Tissier R, Kohlhauer M, Zilberstein L, Blondel M |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Resuscitation
medicine.medical_specialty business.industry Inflammatory response medicine.medical_treatment Veterinary pathology Basic life support 030208 emergency & critical care medicine Limiting 030204 cardiovascular system & hematology Biotechnology 03 medical and health sciences 0302 clinical medicine Human medicine medicine Treatment strategy Cardiopulmonary resuscitation Intensive care medicine business |
| Zdroj: | Journal of Dairy, Veterinary & Animal Research. 3 |
| ISSN: | 2377-4312 |
| DOI: | 10.15406/jdvar.2016.03.00070 |
| Popis: | Animal research is essential to propose new therapeutic approaches limiting the sequels of cardiac arrest in human and veterinary medicine. The ultimate goal is to improve the long term prognosis and neurological recovery. For such investigations, the use of animal models seems unavoidable as cardiac arrest provokes multiple visceral consequences as well as inflammatory response and coagulopathy. These models allow not only a better understanding of the pathophysiology but also the investigation of new treatment strategies to improve basic life support efficiency or prevent multi-organ failure. In this review, we are summarizing the characteristics of the main animal models used in resuscitation sciences. The choice of the species and methods of evaluation of cardiac arrest is crucial. These studies often concern human medicine but they can also address fundamental questions for veterinary research as they are mostly based on animal research. |
| Databáze: | OpenAIRE |
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