| Autor: |
Jessica E. Burch, Austin G. Smith, Seb Caille, Shawn D. Walker, Ryan Wurz, Victor J. Cee, Jose Rodriguez, D. Gostovic, Kyle Quasdorf, Hosea M. Nelson |
| Rok vydání: |
2021 |
| DOI: |
10.26434/chemrxiv-2021-h3tqz |
| Popis: |
The application of microcrystal electron diffraction (microED) to a variety of pharmaceutical compounds is reported. The examples and work detailed showcase the utility of microED as a routine technique for the rapid collection, analysis, and generation of structural data on a number of pharmaceutically relevant compounds, requiring minimal sample preparation and often without the need for time-consuming vitrification and cryo transfer processes. The development of a scripted data processing workflow allowed for simultaneous collection and processing of electron diffraction data, further expediting structural analysis of fifteen compounds. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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