pH-Responsive, two-in-one doxorubicin and Bcl-2 siRNA-loaded micelleplexes for triple-negative breast cancer therapy

Autor:	Hung-Hsun Lu, Hsueh Wen Liu, Trinh Kieu Dinh, Cheng-Hung Huang, Hsi-Chien Huang, Ya-Ching Tseng, Man-Hsuan Ku, Fu-Sheng Wang, Yunching Chen, Chi-How Peng
Rok vydání:	2022
Předmět:	Polymers and Plastics Organic Chemistry Bioengineering Biochemistry
Zdroj:	Polymer Chemistry. 13:5568-5578
ISSN:	1759-9962 1759-9954
Popis:	Triblock copolymer, PEG-b-PDMAEMA-b-PDPA, simultaneously encapsulated doxorubicin and Bcl-2 siRNA for delivery to cancer cells, thus achieving combination chemotherapy and gene therapy.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::ab273c80dd5330f1a93243af25944ff7 https://doi.org/10.1039/d2py00246a Zobrazit plný text záznamu