Inhibitory and Enzyme-Kinetic Investigation of Chelerythrine and Lupeol Isolated fromZanthoxylum rhoifoliumAgainst Krait Snake Venom Acetylcholinesterase

Autor:	Luciana de Carvalho Tavares, Graciane Zanon, Ionara I. Dalcol, Andréia D. Weber, Ademir F. Morel, Mustaq Ahmad, Vinicius Ilha
Rok vydání:	2013
Předmět:	chemistry.chemical_classification Bungarus sindanus biology Traditional medicine Stereochemistry Venom General Chemistry biology.organism_classification complex mixtures Acetylcholinesterase chemistry.chemical_compound Chelerythrine chemistry Triterpene Zanthoxylum rhoifolium Snake venom Lupeol
Zdroj:	Journal of the Brazilian Chemical Society.
ISSN:	0103-5053
Popis:	The in vitro activity of chelerythrine and lupeol, two metabolites isolated from Zanthoxylum rhoifolium were studied against the venom of the snake Bungarus sindanus (Elapidae). The venom, which is highly toxic to humans, consists mainly by the enzyme acetylcholinesterase (AChE). Both compounds showed activity against the venom, and the alkaloid chelerythrine presented higher activity than did triterpene lupeol.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::ab19bce418ebd6e12433c109ecf307fc https://doi.org/10.5935/0103-5053.20130274 Zobrazit plný text záznamu