Association of rs10912745 and rs4916375 polymorphisms located in the cluster of flavin-containing monooxygenase genes, with ischaemic cardioembolic stroke

Autor:	E. A. Bondarenko, Skvortsova Vi, Shetova Im, Svetlana A. Limborska, T. V. Tupitsyna, P. A. Slominsky, D. Yu. Timofeev, N. A. Shamalov
Rok vydání:	2012
Předmět:	Genetics Cardioembolic stroke Single-nucleotide polymorphism Flavin-containing monooxygenase Biology Disease cluster medicine.disease Bioinformatics Genotype medicine Allele Gene Stroke
Zdroj:	Russian Journal of Genetics. 48:572-574
ISSN:	1608-3369 1022-7954
DOI:	10.1134/s1022795412040138
Popis:	Twenty-one SNPs located in the cluster of genes FMO1-FMO2-FMO3-FMO4 and adjacent areas were analyzed in the patients with ischaemic cardioembolic stroke and in the control group. Significant differences between these samples were found in the distribution of genotype and allele differences in two polymorphic loci, rs10912745 and rs4916375. It was shown that these polymorphic loci are associated with the risk of ischaemic cardioembolic stroke development.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::ab14114096b581583a75802a9416a3a4 https://doi.org/10.1134/s1022795412040138 Zobrazit plný text záznamu Full text from SpringerLink