Juvenile hormone action on locust fat body
| Autor: | Kathryn E. Cook, G.R. Wyatt, Helen Firko, Tarlochan S. Dhadialla |
|---|---|
| Rok vydání: | 1987 |
| Předmět: |
medicine.medical_specialty
Methoprene Metabolism Biology biology.organism_classification Biochemistry chemistry.chemical_compound Vitellogenin Endocrinology chemistry Insect Science Internal medicine Juvenile hormone medicine biology.protein Vitellogenesis Corpus allatum Molecular Biology Locust Hormone |
| Zdroj: | Insect Biochemistry. 17:1071-1073 |
| ISSN: | 0020-1790 |
| DOI: | 10.1016/0020-1790(87)90122-3 |
| Popis: | Production of vitellogenin (Vg) in fat body of adult female Locusta migratoria is abolished by removal or inactivation of the corpora allata and restored by administration of (RS)-methoprene. Juvenile hormone III injection alone has little effect, but when it is injected together with the JH esterase inhibitor OTFP, active Vg synthesis is induced. This supports the assumption that methoprene acts in place of the natural hormone in this system. When fat body from vitellogenic females is maintained in synthetic medium for 48 hr, the proportion of Vg in the secreted protein drops greatly, but when methoprene is present in the medium the proportion of Vg is sustained. When fat body from JH-withdrawn locusts, in which Vg synthesis has declined to zero, is cultured with methoprene, Vg synthesis is re-induced. These results show that the JH analog can act directly on locust fat body to bring about expression of the Vg genes. Experiments to optimize JH action on fat body in vitro are continuing. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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