PHOSPHONODIPEPTIDES. SYNTHESIS BY HOBt/DCC METHOD, MASS SPECTRA OF THE PROTECTED AND1H NMR OF THE UNPROTECTED PHOSPHONODIPEPTIDES

Autor:	Bohumil Máca, Miloš Buděšínský, Ivan Lukeš, Petr Hermann
Rok vydání:	1993
Předmět:	Chemistry Stereochemistry Organic Chemistry Diastereomer Nuclear magnetic resonance spectroscopy Condensation reaction Biochemistry Medicinal chemistry Inorganic Chemistry Fragmentation (mass spectrometry) Proton NMR Mass spectrum Protecting group Electron ionization
Zdroj:	Phosphorus, Sulfur, and Silicon and the Related Elements. 79:43-53
ISSN:	1563-5325 1042-6507
DOI:	10.1080/10426509308034396
Popis:	Phosphonodipeptides containing aminomethylphosphonic and 1-aminoethylphosphonic acids were synthesized by the active ester method using N-hydroxybenztriazole and DCC. Fragmentation in electron ionization mass spectra (EI/MS) of protected phosphonodipeptides has been proposed. Results from 1H NMR have shown slightly larger magnetic nonequivalence of—CH2—protons and larger differences in NMR parameters between diastereoisomers than in common dipeptides.
Databáze:	OpenAIRE
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