Synthesis of (arylselanyl)- and (arylsulfenyl)-alkyl-1,2,3-triazolo-1,3,6-triazonines via a copper-catalyzed multicomponent reaction
| Autor: | Ítalo F. C. Dias, José Edmilson R. Nascimento, Thiago Barcellos, Eder J. Lenardão, Gelson Perin, Daniela H. de Oliveira, Thalita F.B. de Aquino, Diego Alves, Raquel G. Jacob |
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| Rok vydání: | 2018 |
| Předmět: |
chemistry.chemical_classification
010405 organic chemistry Chemistry Chemical structure Organic Chemistry chemistry.chemical_element 010402 general chemistry 01 natural sciences Biochemistry Chemical reaction Copper Combinatorial chemistry 0104 chemical sciences Catalysis Drug Discovery Copper catalyzed Alkyl Selenium Copper iodide |
| Zdroj: | Tetrahedron Letters. 59:1080-1083 |
| ISSN: | 0040-4039 |
| DOI: | 10.1016/j.tetlet.2018.01.072 |
| Popis: | An efficient copper-catalyzed multicomponent reaction was developed for the synthesis of (arylselanyl)- or (arylsulfenyl)-alkyl-1,2,3-triazolo-1,3,6-triazonines. The products were obtained in moderate to excellent yields via the reaction of o-phenylenediamine, 2-azidobenzaldehyde and different arylchalcogenyl alkynes using catalytic copper iodide in 1,4-dioxane at 100 °C. The reactions tolerated a range of substituents on the arylchalcogenyl alkynes and proved to be an efficient methodology for the combinatorial synthesis of new selenium or sulfur-containing triazonine derivatives. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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