Synthesis of substituted 5-N-(R)amino-4-cyclohexyl-1-ols by the reaction of secondary enaminones of β-dicarbonyl compounds with chalcones

Autor:	A. Kh. Khachatryan, S. S. Hayotsyan, A. E. Badasyan, M. S. Sargsyan, S. G. Kon’kova
Rok vydání:	2011
Předmět:	chemistry.chemical_compound Primary (chemistry) chemistry Acetylacetone Acetoacetic ester synthesis Organic chemistry General Chemistry
Zdroj:	Russian Journal of General Chemistry. 81:2157-2163
ISSN:	1608-3350 1070-3632
DOI:	10.1134/s1070363211100203
Popis:	Reaction of secondary enaminones of acetylacetone or acetoacetic ester with chalcones at room temperature, is shown to lead to 5-N-(R)amino-4-cyclohexen-1-ols, distinctly to the reaction of the related primary derivatives leading to 1,4-dihydropyridines. Tertiary enaminones of identical structure are found not reacting with chalcones under the similar conditions. The reasons for the difference in the behavior of primary, secondary and tertiary enaminones in the reaction with chalcones are discussed.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::aadd32ff82ffb6e61227f9c35f49c7cb https://doi.org/10.1134/s1070363211100203 Zobrazit plný text záznamu Plný text ve formátu PDF