Forced expiratory manoeuvres provoke nosebleeds and migraines in patients with hereditary haemorrhagic telangiectasia

Autor: Hannah C. Tighe, Lydia Babawale, Claire L. Shovlin, Heidi Wolfenden, J Perks, James Springett, Trishan Patel
Rok vydání: 2016
Předmět:
Zdroj: 9.1 Respiratory Function Technologists/Scientists.
DOI: 10.1183/13993003.congress-2016.pa1326
Popis: Introduction: Forced expiratory manoeuvres during lung function testing produce major pressure swings that are often overlooked by referring clinicians. Standard tests use a noseclip to prevent air leakage through the nose. Our goal was to examine how often the tests caused clinical sequelae such as nosebleeds in people with abnormal nasal and pulmonary vasculature due to hereditary haemorrhagic telangiectasia (HHT). Methods: An international survey was used to identify HHT-affected participants and analyse individuals who had performed forced expiratory manoeuvres either with or without a noseclip in place. Results: 284 HHT-affected respondents were identified. The median age was 54 years (interquartile range 44-62) and the majority were female. All described nosebleeds: 130 (46%) experienced these at least daily, and a further 95 (33%) at least once per week. Only 1 of 253 (0.4%) reported nosebleeds were worse after finger oximetry measurements, compared to 53/282 (18.8%) after “blowing out hard without a noseclip” (χ 2 p Conclusion: Noseclip use should be restricted in people already experiencing regular nosebleeds, and further pretest information may be required.
Databáze: OpenAIRE