The synthesis of 6,9-difluorobenzo[g]quinoline-5,10-dione. Displacements of the fluorides by diamines which lead to 6,9-bis[(aminoalkyl)amino]benzo[g]quinoline-5,10-diones

Autor:	Mary E. Petry, Johanna F. Polsenberg, Roberto Di Domenico, A. Paul Krapcho, John J. Landi, Emesto Menta, John Stallman, Silvano Spinelli, Ambrogio Oliva, Miles P. Hacker
Rok vydání:	1993
Předmět:	chemistry.chemical_compound chemistry Yield (chemistry) Organic Chemistry Quinoline Nucleophilic substitution Electrophilic aromatic substitution Polyamine Medicinal chemistry Quinone
Zdroj:	Journal of Heterocyclic Chemistry. 30:1565-1569
ISSN:	1943-5193 0022-152X
DOI:	10.1002/jhet.5570300619
Popis:	The synthesis of 6,9-difluorobenzo[g]quinoline-5,10-dione (3b) is described. Facile ipso substitutions of the fluorides form (3b) by diamines readily yield the corresponding 6,9-bis[(aminoalkyl)amino]- benzo[g]quinoline-5,10-diones (2). The analogue (2d) has been synthesized by side arm modifications of dione (8a)
Databáze:	OpenAIRE
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