Prediction of paracetamol solubility in cosolvency systems at different temperatures
| Autor: | Elaheh Rahimpour, William E. Acree, Abolghasem Jouyban, Esmail Mohammadian, Ayda Hatefi |
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| Rok vydání: | 2019 |
| Předmět: |
Aqueous solution
Chemistry Solvation Thermodynamics 02 engineering and technology 010402 general chemistry 021001 nanoscience & nanotechnology Condensed Matter Physics 01 natural sciences Atomic and Molecular Physics and Optics 0104 chemical sciences Electronic Optical and Magnetic Materials Solvent Hildebrand solubility parameter Materials Chemistry Physical and Theoretical Chemistry Solubility 0210 nano-technology Spectroscopy |
| Zdroj: | Journal of Molecular Liquids. 273:282-291 |
| ISSN: | 0167-7322 |
| DOI: | 10.1016/j.molliq.2018.10.031 |
| Popis: | The aim of this study is to develop general models based on Abraham solvation parameters and Hansen solubility parameters for the prediction of paracetamol solubility in cosolvency systems at different temperatures. The trained versions of the Jouyban-Acree model, its combined form with the Abraham solvation parameters and the Hansen solubility parameters provide reasonable estimation of the solubility behavior of paracetamol in various solvent mixtures including aqueous and non-aqueous mixtures and can be helpful in the pharmaceutical industry. |
| Databáze: | OpenAIRE |
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