V1. Electric source imaging (ESI) with 10–10 electrodes and individual MRI in presurgical epilepsy monitoring (BESA-Research and BESA-MRI)

Autor: Christian G. Bien, Friedrich G. Woermann, Michael Scherg, Reinhard Schulz
Rok vydání: 2015
Předmět:
Zdroj: Clinical Neurophysiology. 126:e64
ISSN: 1388-2457
DOI: 10.1016/j.clinph.2015.04.079
Popis: Introduction Electric source imaging (ESI) using high-density scalp EEG with at least 128 channels has been reported to accurately localize interictal epileptiform activity. The precision of ESI with 10–10 electrodes has been debated. Method In a pilot study of 10 patients with well defined epileptogenic lesions (focal cortical dysplasia N =4, tumor N =2, unspecified N =2, cavernoma N =1, proliferative oligodendroglial hyperplasia N =1) with focal epilepsy (4 frontal, 2 temporal, 1 parietal, 1 temporoparietal, 1 temporooccipital) we used the presurgical routine of 37–41 scalp electrodes (10–10 system, including inferior electrodes F11, F12, P11, P12) for the source analysis of interictal epileptiform potentials with BESA-Research and for coregistration with the individual MRI (BESA-MRI). Results 9–209 spikes were averaged (mean: 65.9, median: 21, range 9–209; no spikes in 1 patient with FCD so that no source analysis was possible). The location of ESI was 0–1cm to the lesion in 8 patients, 3–4cm to the lesion in 1 patient. Conclusion ESI shows promising results also with a presurgical routine scalp EEG electrode placement. Prospective studies with lesional epilepsies could further define the precision and reliability of this protocol (Plummer et al., 2008; Megevand et al., 2014).
Databáze: OpenAIRE
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