Enantioselective total synthesis of iso-cladospolide B, cladospolide C and cladospolide B from tartaric acid
| Autor: | Kavirayani R. Prasad, Vasudeva Rao Gandi |
|---|---|
| Rok vydání: | 2011 |
| Předmět: |
Cladospolide B
chemistry.chemical_classification Alkene Stereochemistry Organic Chemistry Enantioselective synthesis Total synthesis Metathesis Catalysis Inorganic Chemistry chemistry.chemical_compound Ring-closing metathesis chemistry Amide Tartaric acid Organic chemistry Physical and Theoretical Chemistry |
| Zdroj: | Tetrahedron: Asymmetry. 22:499-505 |
| ISSN: | 0957-4166 |
| DOI: | 10.1016/j.tetasy.2011.02.018 |
| Popis: | The enantioselective synthesis of the natural products cladospolide B, cladospolide C, and iso-cladospolide B has been accomplished from tartaric acid. Key reactions in the synthetic sequence include the elaboration of a gamma-hydroxy amide derived from tartaric acid via alkene cross metathesis, Yamaguchi lactonization, and ring closing metathesis. (C) 2011 Elsevier Ltd. All rights reserved. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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