Benzylic Brominations with N-Bromosuccinimide in (Trifluoromethyl)benzene

Autor:	Claire L. Robinson, Bernard T. Golding, Shang-Min Tu, Dong Jiang, Diana Suarez, Richard Scott, Gilles Laval
Rok vydání:	2009
Předmět:	chemistry.chemical_compound Trifluoromethyl Chemistry Organic Chemistry medicine Azobisisobutyronitrile Radical initiator Benzoyl peroxide N-Bromosuccinimide Benzene Medicinal chemistry Catalysis medicine.drug
Zdroj:	Synthesis. 2009:1807-1810
ISSN:	1437-210X 0039-7881
DOI:	10.1055/s-0029-1216793
Popis:	A variety of benzylic brominations were performed by using N-bromosuccinimide in (trifluoromethyl)benzene with photochemical activation in the presence of 2,2'-azobisisobutyronitrile, 1,1'-azobis(cyclohexanecarbonitrile), or benzoyl peroxide as the radical initiator. This system provides clean, rapid, and high-yielding reactions with replacement of conventional solvents, such as tetrachloromethane, by less-toxic (trifluoromethyl)benzene.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::aa888e817c11ab214bb736f18f1cd41b https://doi.org/10.1055/s-0029-1216793 Zobrazit plný text záznamu