A Gain-of-Function Mutation in a Cytokinin Receptor Triggers Spontaneous Root Nodule Organogenesis

Autor:	Lene H. Madsen, Shusei Sato, Erika Asamizu, Niels Sandal, Leila Tirichine, Jens Stougaard, Simona Radutoiu, Satoshi Tabata, Anita S. Albrektsen
Rok vydání:	2007
Předmět:	Multidisciplinary Root nodule Cell division fungi Mutant Lotus japonicus Histidine kinase food and beverages Organogenesis Biology biology.organism_classification Cell biology chemistry.chemical_compound Biochemistry chemistry Cytokinin Signal transduction
Zdroj:	Science. 315:104-107
ISSN:	1095-9203 0036-8075
Popis:	Legume root nodules originate from differentiated cortical cells that reenter the cell cycle and form organ primordia. We show that perception of the phytohormone cytokinin is a key element in this switch. Mutation of a Lotus japonicus cytokinin receptor gene leads to spontaneous development of root nodules in the absence of rhizobia or rhizobial signal molecules. The mutant histidine kinase receptor has cytokinin-independent activity and activates an Escherichia coli two-component phosphorelay system in vivo. Mutant analysis shows that cytokinin signaling is required for cell divisions that initiate nodule development and defines an autoregulated process where cytokinin induction of nodule stem cells is controlled by shoots.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::aa8621f6db4c511856ced8fcc5cacf49 https://doi.org/10.1126/science.1132397 Zobrazit plný text záznamu Plný text ve formátu PDF