Association Between CHADS2 Score and the Development of Interatrial Block
| Autor: | Xian-Jing Xu, Shan-Ling Wang, Lijie Yan, Jin-Tao Wu, Ying-Jie Chu, De-Yong Long, Xian-Wei Fan, Jian-Zeng Dong, Haitao Yang |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
medicine.medical_specialty
Receiver operating characteristic business.industry Area under the curve Interatrial Block General Medicine Odds ratio medicine.disease Confidence interval Coronary artery disease 03 medical and health sciences 0302 clinical medicine Internal medicine medicine Cardiology Population study 030212 general & internal medicine Cardiology and Cardiovascular Medicine business Stroke 030217 neurology & neurosurgery |
| Zdroj: | International Heart Journal. 59:1261-1265 |
| ISSN: | 1349-3299 1349-2365 |
| DOI: | 10.1536/ihj.17-616 |
| Popis: | Interatrial block (IAB) is associated with a multitude of medical conditions. The aim of this retrospective study was to investigate whether CHADS2 (congestive heart failure, hypertension, age ≥ 75 years, diabetes mellitus, prior stroke) score is positively associated with the development of IAB. A total of 1072 patients (men, 555; women, 517; mean age, 61 ± 14 years) were included in the study. P-wave duration was measured manually using a caliper. IAB was defined as a P-wave duration of ≥ 120 ms on a 12-lead electrocardiogram. CHADS2 scores were calculated retrospectively. Among the 1072 patients, the prevalence of IAB was 36.1% (387/1072). In multivariate analysis, increased CHADS2 score (odds ratio [OR], 1.810; 95% confidence interval [CI], 1.577-2.077; P < 0.001), coronary artery disease (OR, 1.536; 95% CI, 1.065-2.216; P = 0.022), and increased left atrial diameter (OR, 1.039; 95% CI, 1.008-1.071; P = 0.013) were independently associated with IAB. The percentages of patients with IAB among those with a CHADS2 score of 0, 1, 2, 3, 4, 5, and 6 were 20.6%, 33.0%, 45.0%, 55.9%, 61.9%, 77.8%, and 100%, respectively (P < 0.001). There was a greater percentage of patients with a CHADS2 score of ≥ 2 with IAB compared with a CHADS2 score of < 2 (26.5% vsrsus 52.0%; P < 0.001). In receiver operating curve (ROC) analysis, CHADS2 score (area under the curve, 0.670; 95% CI, 0.636-0.704; P < 0.001) was predictive of IAB. In conclusion, CHADS2 score was significantly associated with the development of IAB in this study population. |
| Databáze: | OpenAIRE |
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