Anti-stress effects of rosemary (Rosmarinus officinalis L.) leaf extract on intestinal goblet cells and immobility of forced-swimming test in BALB/c mice
| Autor: | Mituki Umino, Tomoko Kayashima, Hiroko Kaikiri, Kiminori Matsubara, Sachi Shibata, Koji Nagao |
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| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
Microglia biology Chemistry Organic Chemistry Anti stress General Medicine Pharmacology biology.organism_classification Applied Microbiology and Biotechnology Biochemistry Rosmarinus Analytical Chemistry BALB/c 03 medical and health sciences 030104 developmental biology 0302 clinical medicine medicine.anatomical_structure Officinalis medicine Molecular Biology Beneficial effects 030217 neurology & neurosurgery Biotechnology Behavioural despair test |
| Zdroj: | Bioscience, Biotechnology, and Biochemistry. 84:2385-2389 |
| ISSN: | 1347-6947 0916-8451 |
| DOI: | 10.1080/09168451.2020.1800445 |
| Popis: | We investigated the anti-stress effect of rosemary (Rosmarinus officinalis L.) leaf extract (RLE) on restraint-stressed mice and found that RLE alleviated decreases in the number of intestinal goblet cells and amount of hepatic triglycerides. It also decreased the immobility time in the forced-swimming test and activation of microglia in the brain, suggesting that RLE has beneficial effects on stress-induced dysfunctions. |
| Databáze: | OpenAIRE |
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