Clomipramine Treatment and Behaviour Therapy with Agoraphobic Women

Autor:	Whitsett Sf, Troyer Ie, Dalby Jt, David G. Johnston
Rok vydání:	1995
Předmět:	Clomipramine Chemotherapy medicine.medical_specialty Psychotherapist medicine.medical_treatment Exposure therapy Behaviour therapy medicine.disease Placebo Clinical trial Psychiatry and Mental health Internal medicine medicine Psychology Anxiety disorder medicine.drug Agoraphobia
Zdroj:	The Canadian Journal of Psychiatry. 40:192-199
ISSN:	1497-0015 0706-7437
Popis:	The separate and combined effects of clomipramine hydrochlorzide and behaviour therapy on agoraphobic symptoms were investigated in a 28-week placebo-controlled double-blind clinical trial. One hundred and eight women diagnosed as agoraphobic were randomly assigned to one of four treatment conditions: clomipramine alone, behaviour therapy alone, clomipramine and behaviour therapy or placebo. Sixty women completed the assigned treatment. Clomipramine was prescribed in weekly increments to a maximum of 300 mg per day, with a mean dosage at week 8 of 94.6 mg per day. Behaviour therapy focused on graded in vivo exposure therapy. Assessments of patients were performed at six points prior to and during the trial and included standardized questionnaires, daily diaries and a Behavioral Approach Test. Significant main effects for both clomipramine and behaviour therapy on 15 and 12 of the dependent measures respectively were found but no interaction of treatments emerged.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::aa6e2f91da1e3735f6c615b67baa138d https://doi.org/10.1177/070674379504000406 Zobrazit plný text záznamu