Varicella zoster virus encephalopathy in a patient with psoriatic arthritis treated with anti-TNFα agents

Autor: Kenzo Takahashi, Hiroshi Uezato, Takuya Miyagi, Ryo Yasumura, Naoko Nakasone, Aoi Ohira, Yu-ichi Yamamoto, Sayaka Yamaguchi
Rok vydání: 2014
Předmět:
Zdroj: European Journal of Dermatology. 24:398-399
ISSN: 1952-4013
1167-1122
DOI: 10.1684/ejd.2014.2331
Popis: Anti-TNFα agents can favor the development of opportunistic infections with rare pathogens more frequently compared to conventional anti-psoriatic drugs. We report a patient with psoriatic arthritis who developed severe varicella-zoster virus (VZV) encephalopathy after 11 administrations of adalimumab, resulting in permanent higher-brain dysfunction.A 40-year-old Japanese man had been suffering from severe psoriatic arthritis since the age of 22. He was treated with a combination of infliximab and [...]
Databáze: OpenAIRE