Antimicrobial activity of new benzazolyl N-sulfonyl amidines

Autor:	Tetyana Beryozkina, Nadezhda A. Galieva, Dmitriy A. Saveliev, Zhijin Fan, Gert Lubec, Jihong Xing, Oleg S. Eltsov, Vasiliy A. Bakulev
Rok vydání:	2021
Předmět:	Sulfonyl chemistry.chemical_classification chemistry.chemical_compound Acetic acid Ethanol chemistry Substituent Molecule General Chemistry Antimicrobial Medicinal chemistry
Zdroj:	Mendeleev Communications. 31:495-497
ISSN:	0959-9436
Popis:	The reactions of N-(benz[d]oxazol-2-yl)- or N-(benzo[d]-thiazol-2-yl)-substituted carbothioamides with sulfonyl azides proceed as replacement of thioxo substituent by the sulfonylimino group to afford the corresponding N'-sulfonylated amidines. Acetic acid thioamides react smoothly upon boiling in ethanol, while for thioamides of trifluoroacetic and benzoic acids heating to 80–90 °C was required. Among hybrid molecules thus prepared, bacteriostatic-, bactericidal- and fungistatic-active against S. aureus and C. albicans representatives were found.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::aa50e1a629367dc7cfd2a8bb76b62947 https://doi.org/10.1016/j.mencom.2021.07.019 Zobrazit plný text záznamu Full Text from ScienceDirect