Interactions Between Thymosins and Neuroendocrine Circuits

Autor: Robert C. Steiner, Nicholas R.S. Hall, Allan L. Goldstein, Maureen P. O’Grady
Rok vydání: 1988
Předmět:
Zdroj: Neural Development and Regeneration ISBN: 9783642731501
DOI: 10.1007/978-3-642-73148-8_48
Popis: Neuroanatomical and chemical pathways linking the brain with the immune system are now well documented. Coupled with evidence that one’s emotional state can be correlated with an altered level of immune responsiveness, these chemical and neuroanatomical pathways have been regarded as constituting a potential conduit by which the CNS is able to influence the cells and tissues of the immune system. However, a growing body of evidence indicates that the flow of information is not simply unidirectional, but that products of the immune system are capable of modulating several brain mediated events (Hall, et al, 1985). These products include complement proteins, (Schupf, et al., 1983), Interleukin 1 (IL-1) (Krueger, et al., 1984), interferon (Abrams, et al., 1985) as well as thymosin peptides. Table 1 summarizes the CNS mediated activities that these immunotransmitters have been found to exert.
Databáze: OpenAIRE