Monotypic angiomyolipoma of the nasal cavity: An extremely rare cause of nasal mass with recurrent epistaxis
| Autor: | Prajakta A Gupte, Manisha Khare, Yasmeen Khatib, Vinita Pandey, Rahul Pandey |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Microbiology (medical)
Nasal cavity Pathology medicine.medical_specialty Angiomyolipoma business.industry Adipose tissue General Medicine medicine.disease Malignancy Pathology and Forensic Medicine HMB-45 03 medical and health sciences 0302 clinical medicine medicine.anatomical_structure 030220 oncology & carcinogenesis medicine 030211 gastroenterology & hepatology Differential diagnosis business Epithelioid cell Nose |
| Zdroj: | Indian Journal of Pathology and Microbiology. 63:106 |
| ISSN: | 0377-4929 |
| DOI: | 10.4103/ijpm.ijpm_681_18 |
| Popis: | Monotypic angiomyolipoma is usually found in the kidneys and is composed predominantly of epithelioid cells which show positivity for melanocyte and smooth muscle markers. It can pose a diagnostic challenge due to a range of differential diagnosis. We report the second case of monotypic angiomyolipoma of nasal cavity and first from India in a 54-year-old male who presented with a nasal polyp. Grossly the tumor was well circumscribed and un-encapsulated. Microscopy showed a large number of epithelioid cells mixed with a few spindle cells, varying sized blood vessels, and focal areas of adipose tissue. Immunohistochemistry was positive for smooth muscle actin (SMA) and human melanoma black (HMB-45) stains. It is important to identify this tumor as it can sometimes be mistaken for malignancy and only needs endoscopic resection. |
| Databáze: | OpenAIRE |
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