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Santos J, Tjaderhane L, Ferraz C, Zaia A, Alves M, De Goes M, Carrilho M. Long-term sealing ability of resin-based root canal fillings. International Endodontic Journal, 43, 455–460, 2010. Abstract Aim To evaluate the ability of two resin-based filling materials to provide immediate and long-term sealing of the root canal. Methodology A total of eighty-two human roots were instrumented and filled with AH Plus/gutta-percha or Epiphany/Resilon. Root filled teeth were sealed coronally either with Coltosol or Clearfil SE Bond/Filtek Z250 or were left unsealed. The quality of root canal sealing was assessed by a fluid filtration method performed at immediate and 180-day time intervals. Mean fluid filtration rates were analyzed by three-way repeated measures anova and Tukey post hoc test. Results Specimens filled with Epiphany/Resilon exhibited higher leakage than specimens filled with AH Plus/gutta-percha (P 0.05), whilst leakage in teeth without any coronal restoration was significantly higher (P |