Oxidative state and zona-binding ability in mouse spermatozoa treated with reduced glutathione
| Autor: | Shoji Ohta, Kazuhiko Hoshi, Shuji Hirata, Kaoruko Mizuno, Seiichiro Nagai, Tsuyoshi Kasai |
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| Rok vydání: | 2002 |
| Předmět: |
endocrine system
biology urogenital system Cell Biology Glutathione Oxidative phosphorylation Oocyte Protamine Sperm chemistry.chemical_compound medicine.anatomical_structure Human fertilization Reproductive Medicine chemistry Biochemistry biology.protein medicine Nuclear protein Zona pellucida reproductive and urinary physiology |
| Zdroj: | Reproductive Medicine and Biology. 1:55-58 |
| ISSN: | 1445-5781 |
| DOI: | 10.1046/j.1445-5781.2002.00009.x |
| Popis: | Background and Aims Nuclear proteins in mature mammalian spermatozoa nuclei are oxidized to form numerous disulfide bonds. Reduced glutathione (GSH) in the oocyte has been linked to spermatozoan nuclear decondensation after fertilization. In this study, we analyzed whether GSH reduced protamines in sperm nuclei in vitro, and examined the zona-binding ability of treated nuclei. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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