Comparing packing and non-packing of the abscess cavity post incision and drainage of perianal abscess: A meta-analysis
| Autor: | Hussameldin M Nour, Abdul Malik Magsi, Hashim E Elmansi Abdalla, Alexandra Mcwhirter, Ahmed Gadoura, Muhammad S Sajid |
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| Rok vydání: | 2023 |
| Předmět: |
Pharmacology
Ecology Physics and Astronomy (miscellaneous) Physiology General Chemical Engineering Organic Chemistry Biomedical Engineering Pharmaceutical Science General Physics and Astronomy Plant Science General Chemistry Condensed Matter Physics Biochemistry Analytical Chemistry Surfaces Coatings and Films Complementary and alternative medicine Nuclear Energy and Engineering Drug Discovery Molecular Medicine Agronomy and Crop Science Ecology Evolution Behavior and Systematics |
| Zdroj: | Journal of Clinical and Experimental Gastroenterology. 2:8-13 |
| Popis: | Background: Pain is a very important factor in patient recovery and satisfaction. Following incision and drainage of perianal abscess, wound packing has been found to be very painful. The aim of this study is to compare packing the wound and not packing the wound after incision and drainage (I&D) of perianal abscess, taking into account recurrence rate, rate of occurrence of perianal fistula as well as post-operative pain. Materials and Method: Standard medical electronic databases were searched with the help of a local librarian and relevant published randomised controlled trials (RCT) were shortlisted according to the inclusion criteria. The summated outcome of post-operative pain score, recurrence rate, and rate of occurrence of perianal fistula was evaluated using the principles of meta-analysis on RevMan 5 statistical software. Result: Three RCTs on 490 patients undergoing I&D of perianal abscess were found suitable for this meta-analysis. In the random effects model analysis, the post operative pain score was statistically lower in NPG [risk ratio 0.66, 95%, CI (0.36, 0.97), Z=4.25, P=0.0001]. There was no heterogeneity [Tau2=0.15; chi2=9.32; df=6; I2=36 %; p=0.16] between the studies, however, statistically it was not significant. In addition, there was no statistical difference between the 2 groups in terms of recurrence of perianal abscess or the occurrence of perianal fistula [risk ratio 0.64, 95%, CI (0.31, 1.31), Z=1.23, P=0.22], [risk ratio 1.41, 95%, CI (0.89, 2.23), Z=1.47, P=0.14] respectively. Conclusion: Not packing the wound post I&D of perianal abscess is associated with significantly reduced VAS pain scores, which may result in improved recovery and patient satisfaction and has no effect on recurrence rate or the occurrence of perianal fistula. However, more RCTs recruiting a greater number of patients are required to endorse these findings. |
| Databáze: | OpenAIRE |
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