Association of betaxolol therapy with the clinical and functional parameters in patients with essential hypertension

Autor:	A. V. Shabalin, Ye. N. Gulyaeva, A. S. Krikovtsov
Rok vydání:	2005
Předmět:	medicine.medical_specialty business.industry Internal medicine Internal Medicine medicine In patient Cardiology and Cardiovascular Medicine business Essential hypertension medicine.disease Betaxolol medicine.drug
Zdroj:	"Arterial’naya Gipertenziya" ("Arterial Hypertension"). 11:261-264
ISSN:	2411-8524 1607-419X
DOI:	10.18705/1607-419x-2005-11-4-261-264
Popis:	The association of clinical and functional parameters was studied in patients with mild and moderate arterial hypertension (All) during therapy with betaxolol (Lokren), Twenty six patients (19 males and 7 females) aged 28 to 56 (mean 40.5 ± 1.4) years who had grade 1-2 AH were examined. The patients received monotherapy with betaxolol in a single dose of 10 mg/day. 24-hour ECG and blood pressure monitoring, stress-echocardiography during the arithmetic test estimating cognitive functions and life quality by the SP-36 scale were performed at the baseline and following 8 weeks of therapy. It has been found that betaxolol (Lokren) used In a single dose of 10 mg/day for 8 weeks has a high antihypertensive efficacy, stabilizes the autonomic balance of cardiac rhythm regulation, by simultaneously showing antiarrhythmic properties, reduces the degree of stress responsiveness, and enhances the inhibition of the central nervous system, by ultimately improving the quality of life in the patients.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::aa20ee8496de11f1f5494001922e38dc https://doi.org/10.18705/1607-419x-2005-11-4-261-264 Zobrazit plný text záznamu