Fusariumspp.—An Emerging Pathogen in Chronic Diabetic Ulcer: Case Report and Review of the Literature
| Autor: | José Neves, Ana Formiga, Tomás Pessoa E Costa, Ana Luísa João, André Lencastre, Eduardo Dutra |
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| Rok vydání: | 2019 |
| Předmět: |
Fusariosis
Voriconazole medicine.medical_specialty business.industry medicine.medical_treatment 030231 tropical medicine General Medicine Disease medicine.disease Revascularization Dermatology Diabetic foot 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine Diabetic foot ulcer Amputation medicine Surgery Differential diagnosis business medicine.drug |
| Zdroj: | The International Journal of Lower Extremity Wounds. 20:67-72 |
| ISSN: | 1552-6941 1534-7346 |
| DOI: | 10.1177/1534734619879030 |
| Popis: | The genus Fusarium is ubiquitous in the environment and has been emerging as an opportunistic human pathogen. We report the case of a 65-year-old man with a history of neuroischemic, otherwise unamenable to revascularization, diabetic foot, who was admitted due to an infected deep foot ulcer. Despite conventional antibiotic and wound care treatment, no improvement was initially observed. A reappraisal of the diagnosis, with microbiological and histological analyses, documented infection of the foot ulcer with Fusarium oxysporum. Clinical improvement was noted under prolonged oral voriconazole therapy. The present case broadens the differential diagnosis of diabetic foot infection. Subcutaneous fusariosis should be considered in recalcitrant infected diabetic ulcers, as early diagnosis and management may help prevent amputation and life-threatening disease. |
| Databáze: | OpenAIRE |
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