Efficient Synthesis of Water-Soluble Alkyl-bis(m-sulfonated-phenyl)- and Dialkyl-(m-sulfonated-phenyl)-phosphines and Their Evaluation in Rhodium-Catalyzed Hydrogenation of Maleic Acid in Water
| Autor: | László T. Mika, István T. Horváth, László Orha, Norbert Farkas |
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| Rok vydání: | 2009 |
| Předmět: |
chemistry.chemical_classification
Aqueous solution Maleic acid Organic Chemistry chemistry.chemical_element Ph measurement Medicinal chemistry Rhodium Catalysis Inorganic Chemistry chemistry.chemical_compound Water soluble chemistry Organic chemistry Physical and Theoretical Chemistry Alkyl Phosphine |
| Zdroj: | Organometallics. 28:1593-1596 |
| ISSN: | 1520-6041 0276-7333 |
| Popis: | The combined application of 31P NMR and pH measurements during the tri-isooctylamine-assisted aqueous/organic separation and purification steps after the sulfonation of diphenyl-alkyl-phosphines (Ph2PR; R = Me, n-Bu) and phenyl-dialkyl-phosphines (PhPR2; R = Me, n-Bu) resulted in the preparation of water-soluble alkyl-bis(m-sulfonated-phenyl)- (C6H4-m-SO3Na)2PR; R = Me, n-Bu) and dialkyl-(m-sulfonated-phenyl)- (C6H4-m-SO3Na)PR2; R = Me, n-Bu) phosphines in the presence of less than 0.5% phosphine oxides. When 2 equiv of the water-soluble phosphines were used per rhodium atom, no significant effect on the turnover frequency of the hydrogenation of maleic acid can be observed by using these phosphines. |
| Databáze: | OpenAIRE |
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