Structure and chromosome mapping of the human SIX4 and murine Six4 genes

Autor: S. Asakawa, K. Kawakami, M. Kobayashi, N. Shimizu, S. Minoshima, K. Yamada, H. Ozaki, M. Kajitani
Rok vydání: 1999
Předmět:
Zdroj: Cytogenetic and Genome Research. 87:108-112
ISSN: 1424-859X
1424-8581
DOI: 10.1159/000015407
Popis: Six4, a member of the homeobox gene subfamily (Six), is expressed in a developmentally regulated fashion, and supposed to be involved in embryogenesis. We cloned the human SIX4 and murine Six4 genomic DNAs and determined their structures. The structure, including the 5′ upstream region of both genes, was well conserved suggesting the conserved function and regulation of these genes. Human SIX4 was mapped to chromosome 14q23.
Databáze: OpenAIRE