Facile synthesis of 2-(2-arylpyrrolidin-1-yl)pyrimidines via acid-catalyzed reaction of N-(4,4-diethoxybutyl)pyrimidin-2-amine with phenols

Autor:	Alexander R. Burilov, V. V. Syakaev, Almir S. Gazizov, Michail A. Pudovik, Andrey V. Smolobochkin, N. I. Kharitonova
Rok vydání:	2015
Předmět:	chemistry.chemical_compound Pyrimidine Chemistry Intramolecular force Acid catalyzed One-pot synthesis Phenol Organic chemistry Amine gas treating General Chemistry Phenols Pyrrolidine
Zdroj:	Monatshefte für Chemie - Chemical Monthly. 146:1845-1849
ISSN:	1434-4475 0026-9247
Popis:	N-(4,4-diethoxybutyl)pyrimidin-2-amine undergoes acid-catalyzed intramolecular cyclisation in the presence of phenols leading to the formation of 2-(2-arylpyrrolidin-1-yl)pyrimidine derivatives. Target compounds were obtained with moderate to good yields by operationally simple one-step procedure.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::a9e3430f58e21bb10dfa9cafcfae3ef6 https://doi.org/10.1007/s00706-015-1545-1 Zobrazit plný text záznamu Full text from SpringerLink