Influence of hot alcohol extraction of Celery fruits on renal stones dissolution in vitro

Autor: Saad H. Khudier, Duha B. Mohamed, Nibal Kh. Mousa, Shahad Sh. Sabbar
Rok vydání: 2014
Předmět:
Zdroj: Journal of Biotechnology Research Center. 8:71-76
ISSN: 2708-1370
1815-1140
DOI: 10.24126/jobrc.2014.8.1.312
Popis: This study was carried out to investigate the effect of hot alcohol extraction activity of Apium graveolens fruits on the common Renal stones dissolution (Ca-OX ,Uric acid) kinds and volatile oils concentrations on Apium graveolens via HPLC were estimated. Fourteen compounds which were (α-pinene, Cineole, P- cymene, Terpinene, α- phellandrene, β-pinene, Geraneole, α-terpinole, Linalool, Menthone, Limonene, Myrcene, Camphen, Rutin) were measured. In regard to concentration, α -pinene has the highest concentration since it reaches 19.2 µg/ml, while the lower concentration was achieved with Camphen which was 6.3 µg/ml. Results of Ca-Ox renal stones treated with extract of Apium graveolens showed significant decrease in stone weight since highest weight decrease percentage, using the hot alcoholic extract reaches 17.02 % at 5 % concentration and in comparison with Rowantinex drug, the results showed a high similitude between the hot alcoholic extract at 5% concentration and Rowantinex drug in respect of percentage of renal stones dissolution, so hot alcohol extraction of apium gravedens in 5% concentration was the best and active in dissolution Ca-OX at first degree and uric acid at second degree.
Databáze: OpenAIRE