Influence of hot alcohol extraction of Celery fruits on renal stones dissolution in vitro
Autor: | Saad H. Khudier, Duha B. Mohamed, Nibal Kh. Mousa, Shahad Sh. Sabbar |
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Rok vydání: | 2014 |
Předmět: | |
Zdroj: | Journal of Biotechnology Research Center. 8:71-76 |
ISSN: | 2708-1370 1815-1140 |
DOI: | 10.24126/jobrc.2014.8.1.312 |
Popis: | This study was carried out to investigate the effect of hot alcohol extraction activity of Apium graveolens fruits on the common Renal stones dissolution (Ca-OX ,Uric acid) kinds and volatile oils concentrations on Apium graveolens via HPLC were estimated. Fourteen compounds which were (α-pinene, Cineole, P- cymene, Terpinene, α- phellandrene, β-pinene, Geraneole, α-terpinole, Linalool, Menthone, Limonene, Myrcene, Camphen, Rutin) were measured. In regard to concentration, α -pinene has the highest concentration since it reaches 19.2 µg/ml, while the lower concentration was achieved with Camphen which was 6.3 µg/ml. Results of Ca-Ox renal stones treated with extract of Apium graveolens showed significant decrease in stone weight since highest weight decrease percentage, using the hot alcoholic extract reaches 17.02 % at 5 % concentration and in comparison with Rowantinex drug, the results showed a high similitude between the hot alcoholic extract at 5% concentration and Rowantinex drug in respect of percentage of renal stones dissolution, so hot alcohol extraction of apium gravedens in 5% concentration was the best and active in dissolution Ca-OX at first degree and uric acid at second degree. |
Databáze: | OpenAIRE |
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