Cardio-Toxicity during chemotherapy: feasibility of new diagnostic approaches

Autor:	Fable Zustovich, Rosanna Canton, Renato Ceravolo, Martina Zaninotto, Mario Trivellato, Monica Maria Mion, Mario Plebani, Giuseppe Cartei, Martina Mattiazzi, Davide Pastorelli, Lorena Buratin
Rok vydání:	2010
Předmět:	Oncology Blood level Chemotherapy medicine.medical_specialty Side effect business.industry medicine.medical_treatment Brain natriuretic peptide Surgery Clinical trial Chemotherapy induced Fluorouracil Internal medicine medicine Cardio toxicity business medicine.drug
Zdroj:	Health. :376-380
ISSN:	1949-5005 1949-4998
DOI:	10.4236/health.2010.24056
Popis:	Chemotherapy induced cardio-toxicity is a well known side effect of anticancer treatments, moreover the 70% of all tumors involve patients over 65 years-old, frequently with cardiac co- morbidity. We evaluated the feasibility of the application during chemotherapy administration of some of the most recent diagnostic techniques as 12-diagnostic leads telemetry, 7 days EKG monitoring device (R-Test Evolution 3R), blood level dosage of Brain Natriuretic Peptide (BNP) and Ischemia Modified Albumin (IMA). Some sub-clinical changes in the investigated parameters were found in patients undergoing chemotherapy, mostly containing fluorouracil, as shown in the following paper. Far from suggesting a widespread use of these methods during chemotherapy administration, we think that some more tools are needed to prevent cardiac toxicity in high-risk patients and some of what we studied may deserve further valuation in chemotherapy clinical trials.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::a9d35346991500ab0f5dd48e30b3fa90 https://doi.org/10.4236/health.2010.24056 Zobrazit plný text záznamu