| Popis: |
The isolation of human DNA sequences that encode immunoglobulin genes, T cell receptor genes, and protooncogenes involved in the pathogenesis of lymphoid neoplasms has provided highly sensitive molecular probes to determine clonality and lineage in lymphopro-liferative lesions. The application of these probes to diagnostic problems in pathology has enhanced greatly the ability of the pathologist to determine clonality and lineage in lymphoid neoplasms, distinguish lymphoid from non-lymphoid tumors, monitor minimal residual disease, and identify early relapse. |
