Clostridium difficile infection in hospitalized octogenarian patients
| Autor: | Tudor Cuciureanu, Camelia Cojocariu, Egidia Miftode, Stefan Chiriac, Ana-Maria Singeap, Carol Stanciu, Catalin Sfarti, Oana Stoica, Irina Girleanu, Anca Trifan |
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| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty Chronic cardiac failure business.industry medicine.drug_class 030106 microbiology Antibiotics Severe disease Clostridium difficile medicine.disease Logistic regression Surgery 03 medical and health sciences 0302 clinical medicine Internal medicine medicine 030212 general & internal medicine Antibiotic use business Hospital stay Kidney disease |
| Zdroj: | Geriatrics & Gerontology International. 18:315-320 |
| ISSN: | 1444-1586 |
| Popis: | Aim To evaluate the risk factors and outcome of Clostridium difficile infection in hospitalized octogenarian patients. Methods A retrospective analysis of risk factors and outcome of C. difficile infection in hospitalized octogenarians was carried out at two academic centers in Romania from January 2014 to September 2016. Demographic, clinical and laboratory characteristics; antibiotics and proton pump inhibitors use in-hospital and 2 months before admission; comorbidities; length of hospital stay; treatment; and outcome were carefully collected from the patients’ medical charts and compared with those from octogenarians hospitalized during the same period. Results A total of 286 octogenarians were hospitalized during the study period and among them 79 (27.6%) were diagnosed with C. difficile infection. On multivariate logistic regression analyses, the previous 2 months’ hospitalizations (OR 10.231, 95% CI 1.769–58.965, P = 0.009), antibiotic use 2 months before admission (OR 12.596, 95% CI 1.024–15.494, P = 0.048), antibiotic treatment during hospitalization (OR 6.302, 95% CI 3.510–11.316, P |
| Databáze: | OpenAIRE |
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