Factors affecting degree of sedation after intracarotid amytal injection

Autor: Jennifer J. Bortz, Tajammul Ehsan, David Blum
Rok vydání: 1997
Předmět:
Zdroj: Journal of Epilepsy. 10:42-46
ISSN: 0896-6974
DOI: 10.1016/s0896-6974(96)00064-3
Popis: The intraarterial amytal procedure (IAP) is used to assess hemispheric support for language and memory. The test requires producing hemianesthesia without rendering the patient unconscious. We retrospectively studied factors that relate to undersedation and oversedation in the IAP in 52 patients. Initial amytal dose was 125 mg. To reduce angiographic risk, injections were performed only ipsilateral to the side of planned surgery unless injection results were unclear. Overall, 31% of patients were judged to be “undersedated” due to excessively brief duration of amytal response; 15% were “oversedated” to the point of inattentiveness or unconsciousness during the test. Patients with mesial temporal sclerosis (MTS) manifest on magnetic resonance imaging (MRI) were more than twice as likely to have excessive sedation as compared with patients with normal MRI results or with lesions. All patients with mixed dominance were oversedated (100%), and patients with nondominant injection were less likely to be oversedated (4%) than patients with dominant injections (14%). Patients with Full-Scale IQ (FSIQ)
Databáze: OpenAIRE