POS1249 MULTISYSTEM INFLAMMATORY SYNDROME IN CHILDREN DURING THE COVID-19 PANDEMIC IN TURKEY: FIRST REPORT FROM THE EASTERN MEDITERRANEAN
| Autor: | Sibel Laçinel Gürlevik, Jale Karakaya, Yasemin Ozsurekci, Selman Kesici, U. Kaya Akca, Seza Ozen, Ali Bülent Cengiz, B. Katlan, Pembe Derin Oygar, Kubra Aykac, Benan Bayrakci, Sare Ilbay, B. C. Cura Yayla, O. Saritas Nakip, Mehmet Ceyhan, Yelda Bilginer, Özge Başaran, D. Karacanoglu |
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| Rok vydání: | 2021 |
| Předmět: |
myalgia
Pediatrics medicine.medical_specialty Abdominal pain business.industry Immunology Peripheral edema Disease medicine.disease Rash General Biochemistry Genetics and Molecular Biology Lymphoma medicine.anatomical_structure Rheumatology White blood cell Pandemic medicine Immunology and Allergy medicine.symptom business |
| Zdroj: | Annals of the Rheumatic Diseases. 80:908.1-908 |
| ISSN: | 1468-2060 0003-4967 |
| DOI: | 10.1136/annrheumdis-2021-eular.3572 |
| Popis: | Background:The severity of COVID-19 symptoms can range from mild to severe. Severe COVID-19 cases with excessive hyperinflammation have many overlap features with multisystem inflammatory syndrome in children (MIS-C).Objectives:We aimed to describe the typical clinical and laboratory features and treatment of children diagnosed with MIS-C and to understand the differences as compared to severe/critical pediatric cases with COVID-19 in an eastern Mediterranean country.Methods:Children (aged Results:A total of 52 patients, 22 patients diagnosed with COVID-19 with severe/critical disease course and 30 patients diagnosed with MIS-C. Although severe COVID-19 cases and cases with MIS-C share many clinical and laboratory features, MIS-C cases had longer fever duration and higher rate of the existence of rash, conjunctival injection, peripheral edema, abdominal pain, altered mental status, and myalgia than in severe cases (pConclusion:Differences between clinical presentations, acute phase responses, organ involvements, and management strategies indicate that MIS-C might be a distinct immunopathogenic disease as compared to pediatric COVID-19. Conjunctival injection and higher CRP and low WBC count seem good diagnostic parameters for MIS-C cases.Disclosure of Interests:None declared |
| Databáze: | OpenAIRE |
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