Mycobacterium bovis-induced Aneurysm after Intravesical Bacillus Calmette-Guérin Therapy: A Case Study and Literature Review
| Autor: | Yoshitsugu Higashi, Shigeki Nakamura, Yoshihiro Yamamoto, Kento Kidani, Yukio Kawagishi, Junko Isobe, Ippei Sakamaki, Kaoru Matumoto, Jun-ichi Kanatani, Koyomi Kawago |
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| Rok vydání: | 2018 |
| Předmět: |
medicine.medical_specialty
Mycobacterium bovis Bladder cancer biology business.industry General Medicine 030204 cardiovascular system & hematology medicine.disease biology.organism_classification Gastroenterology 03 medical and health sciences Aortic aneurysm 0302 clinical medicine Aneurysm Internal medicine Multiplex polymerase chain reaction Internal Medicine medicine Intravesical bacillus Calmette-Guerin Sputum 030212 general & internal medicine medicine.symptom business BCG vaccine |
| Zdroj: | Internal Medicine. 57:429-435 |
| ISSN: | 1349-7235 0918-2918 |
| DOI: | 10.2169/internalmedicine.9102-17 |
| Popis: | Mycobacterium bovis infection after intravesical Bacillus Calmette-Guerin (BCG) therapy is rare. A 65-year-old Japanese man with history of bladder cancer and intravesical BCG therapy, presented with low-grade fever. An aneurysm with perianeurysmal fluid was suspected and endovascular aortic repair was performed. After 160 days, he developed blood-streaked sputum and computed tomography images revealed that the perianeurysmal fluid area was increasing in size. A multiplex polymerase chain reaction using sputum identified M. bovis. Treatment with anti-tuberculosis drugs reduced the size of the perianeurysmal fluid area. After intravesical BCG therapy, the possibility of M. bovis infection should be considered, thus further investigations are required. |
| Databáze: | OpenAIRE |
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