| Popis: |
The oxazaphopholidine borano complex 3 , prepared in one step from ephedrine, reacts with alkyl and aryl lithium compounds to afford regio and stereoselectively the corresponding aminophosphine complexes 4 . Acid methanolysis of 4 leads to the phosphinite borane complexes 5 which are used for the preparation of the mono and diphosphine boranes 6 , 8 , and subsequently the corresponding phosphines 7 , 9 alter decomplexation with Et2NH. The preparation of (+) and (−)-PAMP 7a , DIPAMP 9a or β-BNPE 9b from the same complex 3 is described. |
