Mechanism of citrinin-induced dysfunction of mitochondria. VI. Effect on iron-induced lipid peroxidation of rat liver mitochondria and microsomes

Autor:	Annibal P. Campello, Generoso M. Chagas, Ma. Lúcia W. Klüppel, Sonia M. R. Ribeiro
Rok vydání:	1998
Předmět:	inorganic chemicals animal structures Rat liver mitochondria Clinical Biochemistry Cell Biology General Medicine Mitochondrion Biochemistry Citrinin Lipid peroxidation chemistry.chemical_compound chemistry Microsome Chelation Mycotoxin
Zdroj:	Cell Biochemistry and Function. 16:15-20
ISSN:	1099-0844 0263-6484
DOI:	10.1002/(sici)1099-0844(199803)16:1<15::aid-cbf756>3.0.co;2-p
Popis:	The inhibition by citrinin (CTN) of lipid peroxidation of mitochondria, sub-mitochondrial particles (SMP) and microsomes was studied. This effect was reversed by the presence of high concentrations of Fe3+ (0·4 and 0·5 mM), suggesting chelation of the mycotoxin with iron or interference in the reduction of Fe3+. © 1998 John Wiley & Sons, Ltd.
Databáze:	OpenAIRE
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