Age at onset and the outcomes of schizophrenia: A systematic review and meta-analysis

Autor: Jouko Miettunen, Hanna Korpela, Johanna Immonen, Erika Jääskeläinen
Rok vydání: 2017
Předmět:
Zdroj: Early Intervention in Psychiatry. 11:453-460
ISSN: 1751-7885
DOI: 10.1111/eip.12412
Popis: The aim of this study was to analyse the effect of age at onset on the long-term clinical, social and global outcomes of schizophrenia through a systematic review and a meta-analysis. Original studies were searched from Web of Science, PsycINFO, Pubmed and Scopus, as well as manually. Naturalistic studies with at least a 2-year follow-up were included. Of the 3509 search results, 81 articles fulfilled the inclusion criteria. The meta-analysis was performed in Stata as a random-effect analysis with correlation coefficients between age at onset and the outcomes (categorized into remission, relapse, hospitalization, positive symptoms, negative symptoms, total symptoms, general clinical outcome, employment, social/occupational functioning and global outcome). There was a statistically significant (P
Databáze: OpenAIRE
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