Convenient method for the synthesis of phthalazinones via carbonylation of 2-bromobenzaldehyde using Co2(CO)8 as a CO source

Autor:	A. Sivalingam Suresh, Mansur Ahmed, Poongavanam Baburajan
Rok vydání:	2014
Předmět:	Chemistry Organic Chemistry Drug Discovery Condensation chemistry.chemical_element Biochemistry Carbonylation Combinatorial chemistry Palladium
Zdroj:	Tetrahedron Letters. 55:3482-3485
ISSN:	0040-4039
DOI:	10.1016/j.tetlet.2014.04.082
Popis:	A simple one-pot synthesis of phthalazinones by the condensation and intra-molecular carbonylative cyclization of 2-bromobenzaldehydes with hydrazines is reported. This method utilizes solid Co2(CO)8 as carbonyl source making it readily accessible in small-scale laboratory applications.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::a8fa948bcb37fb85f0497d319aae51c6 https://doi.org/10.1016/j.tetlet.2014.04.082 Zobrazit plný text záznamu Full Text from ScienceDirect