Three cases of Pulmonary Epithelioid Hemangioendothelioma
| Autor: | Kyung Chan Kim, Seung Hyun Lee, Sun Hyo Park, Young June Jeon, Seung Beom Han, Kun Young Kwon, Min Soo Kim, Chang Gyun Seo |
|---|---|
| Rok vydání: | 2002 |
| Předmět: |
Pulmonary and Respiratory Medicine
medicine.medical_specialty Pathology Lung Pleural effusion business.industry Pulmonary insufficiency Soft tissue Nodule (medicine) Malignancy medicine.disease Staining Infectious Diseases medicine.anatomical_structure medicine Immunohistochemistry Radiology medicine.symptom business |
| Zdroj: | Tuberculosis and Respiratory Diseases. 53:56 |
| ISSN: | 0378-0066 |
| Popis: | A pulmonary epithelioid hemangioendothelioma (PEH) is a rare tumor with a vascular origin. A PEH can arise in many organ systems, such as the lung, liver, bone and soft tissues. It is a borderline malignancy but the clinical course is usually benign. In this report, we describe three cases of PEH. Case 1, a 61-year-old man, had nonspecific chest discomfort and the chest X-ray showed a solitary lung nodule. This nodule was diagnosed by an open lung biopsy. The pathologic findings including abundant necrosis, mitosis and hyperchromatic and pleomorphic nuclei, indicated a malignancy. The electron microscopic study showed Weibel-Palade bodies and the immunohistochemical stain for CD31 showed a positive reaction in the tumor cells, and linear staining along the vascular lumina. Case 2, a 34-year-old man, was admitted for an evaluation of multiple small nodules, incidentally detected a screening chest X-ray. The nodules were diagnosed by a immunohistochemical stain for the factor VIII-related antigen. Case 3, a 34-year-old woman, complained of left pleuritic chest pain. A simple chest film and the chest CT scan revealed multiple bilateral nodules and a left pleural effusion. An immunohistochemical stain for the factor VIII-related antigen was used to diagnose the nodules. Forth-one months after the diagnosis, she died of pulmonary insufficiency. |
| Databáze: | OpenAIRE |
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