| Popis: |
A convenient method for synthesis of novel 1-[pyrimidinyl], 1-[1,3,5-triazin-2-carbonyl], and 1-[thiazol-5-carbonyl] derivatives of 3-thioxo-diaziridine , , , and from corresponding hydrazides, CS2, and KOH is elaborated. The highest reaction yield was observed when these initial reagents were taken in molar ratio of 1:1.7:2.0, respectively. By alkylation of compounds , , , and that proceeds exclusively at sulfur atom, the 3-sulfanyl derivatives of 1-[pyrimidinyl]-, 1-[1,3,5-triazin-2-carbonyl]-, and 1-[thiazol-5-carbonyl]-diazirines , , , and were formed. The structures of synthesized compounds were confirmed by proton and carbon nuclear magnetic resonance (NMR), mass spectra (MS), and elemental analysis. The fungicidal activities of S-substituted derivatives were studied. Data of preliminary biological tests testify that these compounds can be of interest in search for new fungicides. J. Heterocyclic Chem., (2010). |
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