64-jährige Patientin mit perianalen Blutabgängen, chronischer Diarrhö und schwerer Stuhlinkontinenz

Autor:	Allgayer H, Dietrich Cf
Rok vydání:	2009
Předmět:	CREST Syndrome Gastrointestinal bleeding medicine.medical_specialty Lower gastrointestinal bleeding Malabsorption business.industry Stomach Gastroenterology Rectum medicine.disease medicine.anatomical_structure Internal medicine Medicine Fecal incontinence Angiodysplasia medicine.symptom business
Zdroj:	Zeitschrift für Gastroenterologie. 47:361-364
ISSN:	1439-7803 0044-2771
Popis:	Unclear perianal bleeding may cause diagnostic and therapeutic difficulty, particularly when the bleeding source cannot be detected. In this case record we report on a 64-year-old woman with systemic sclerosis and incomplete CRES(T) syndrome diagnosed more than 10 years ago with no detectable teleangiectasia/angiodysplasia at that time. During the course of the disease the initially incomplete CRES(T) syndrome developed into a complete CREST syndrome with repeated bleeding from teleangiectatic/angiodysplastic lesions of the rectum, stomach/duodenum. In addition, chronic diarrhoea with malabsorption, bacterial overgrowth and severe anal incontinence were present which all were seen as intestinal manifestations of the existing underlying disease. A complete motoric and sensoric insufficiency of the anal sphincter was found manometrically, anal endosonography with elastography revealed changes compatible with sclerosis. In the absence of a causal therapy symptomatic treatment stratgies are described and discussed on the basis of exisitng pathophysiologic knowledge.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::a8c586c6e936ee2b02706a9d0e32b799 https://doi.org/10.1055/s-2008-1027703 Zobrazit plný text záznamu