Synthesis of enantiopure (nor-)azatropanes viaN-acylhydrazonium ion intermediates

Autor:	W. Nico Speckamp, Henk Hiemstra, N.Miranda Teerhuis
Rok vydání:	1997
Předmět:	Enantiopure drug Chemistry Organic Chemistry Drug Discovery Organic chemistry Stereoselectivity Key features Biochemistry Ion
Zdroj:	Tetrahedron Letters. 38:155-158
ISSN:	0040-4039
Popis:	The synthesis of a number of aza-analogues of (nor)tropanes is described. Key features of the synthesis include the efficient preparation of an enantiopure 5-substituted 3-pyrazolidinone and stereoselective cyclization of an N-acylhydrazonium ion intermediate.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::a8bf85b9786b8b18044a294d8cde5752 https://doi.org/10.1016/s0040-4039(96)02241-1 Zobrazit plný text záznamu Full Text from ScienceDirect