Pd-catalyzed hydroaminocarbonylation of alkynes with aliphatic amines and its mechanism study

Autor:	Ye Liu, Wen-Yu Liang, Lei Liu, Dong-Liang Wang, Qing Zhou, Wen-Di Guo, Yong Lu
Rok vydání:	2019
Předmět:	010405 organic chemistry Chemistry Regioselectivity 010402 general chemistry 01 natural sciences Combinatorial chemistry Catalysis Mechanism (sociology) 0104 chemical sciences
Zdroj:	Catalysis Science & Technology. 9:1334-1337
ISSN:	2044-4761 2044-4753
DOI:	10.1039/c8cy02337a
Popis:	This work describes the hydroaminocarbonylation of alkynes with aliphatic amines without the addition of any acid additive. Excellent conversion and regioselectivity toward the formation of branched amides were obtained over a dppp-based Pd-catalytic system. The catalytic mechanism was studied and disclosed that the carbamoylpalladium complex intermediate instead of the widely accepted palladium-hydride (Pd–H) species was the active catalytic species for this reaction.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::a8b2aaf6cd7467e683993088338e2f8a https://doi.org/10.1039/c8cy02337a Zobrazit plný text záznamu