Preliminary evaluation of an immunoturbidimetric assay and lateral flow device for the measurement of serum amyloid A in rabbits

Autor: Angela M. Lennox, Kristopher L. Arheart, Carolyn Cray, Takuo Ichiyanagi, Yukari Asahi
Rok vydání: 2020
Předmět:
Zdroj: Journal of Exotic Pet Medicine. 33:54-56
ISSN: 1557-5063
Popis: Background: Acute phase proteins (APPs) can provide a sensitive test option for detection of inflammation in companion and large animals as well as many nondomesticated mammals. While some basic science studies have addressed APPs expression in rabbits, modern methods have not been widely applied to the detection of inflammation in this species. Methods: In this study, an automated immunoturbidimetric assay for serum amyloid A (SAA) was evaluated. Results: The median (min-max) SAA level of clinically normal rabbits was 6.3 (6.3–24.2) mg/L versus 7.0 (6.3–1388.0) mg/L for the abnormal group. The assay results were also compared to a previously described assay for C-reactive protein (CRP) and found correlated (r = 0.76, P
Databáze: OpenAIRE