Autor:	Margeris Lidaks, M. Madre, R. Zhuk
Rok vydání:	1991
Předmět:	viruses virus diseases Prodrug Biochemistry Combinatorial chemistry Virology chemistry.chemical_compound chemistry Genetics medicine Aciclovir Solubility skin and connective tissue diseases Derivative (chemistry) medicine.drug
Zdroj:	Nucleosides and Nucleotides. 10:279-282
ISSN:	0732-8311
Popis:	A series of 0-alkoxyalkyl ethers of aciclovir (ACV) have been synthesized in the reaction of 9-[2-hydroxyethoxymethy1]-N2-acetylgua-nine and its 8-bromo derivative with a-vinylethers. The compounds are characterized by much higher solubility as compared with ACV and display very good antiviral activity against HSV-1 in mice.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::a87065c7d504bb12ba2d5ee5d2fc91ea https://doi.org/10.1080/07328319108046459 Zobrazit plný text záznamu