Cross-national epidemiology of panic disorder and panic attacks in the world mental health surveys

Autor:	Guilherme Borges, Margreet ten Have, Jose Posada-Villa, Carmen C.W. Lim, Daphna Levinson, Annelieke M. Roest, Ronald C. Kessler, Viviane Kovess-Masfety, Yolanda Torres, Koen Demyttenaere, Ali Al-Hamzawi, Noboru Iwata, Giovanni de Girolamo, Kate M. Scott, Aimee N. Karam, Meredith Harris, Evelyn J. Bromet, Silvia Florescu, Maria Carmen Viana, Fernando Navarro-Mateu, Jacek Moskalewicz, Josep Maria Haro, Marina Piazza, Oye Gureje, Siobhan O'Neill, Dan J. Stein, Peter de Jonge, José Miguel Caldas-de-Almeida, Vladimir Nakov, Chiyi Hu, Sing Lee, Mark Anthony Oakley Browne
Rok vydání:	2016
Předmět:	education.field_of_study medicine.medical_specialty Panic disorder Population Panic Context (language use) medicine.disease 030227 psychiatry 03 medical and health sciences Psychiatry and Mental health Clinical Psychology 0302 clinical medicine medicine Anxiety medicine.symptom Age of onset education Psychiatry Psychology 030217 neurology & neurosurgery Psychopathology Agoraphobia
Zdroj:	Depression and Anxiety. 33:1155-1177
ISSN:	1091-4269
DOI:	10.1002/da.22572
Popis:	Context The scarcity of cross-national reports and the changes in Diagnostic and Statistical Manual version 5 (DSM-5) regarding panic disorder (PD) and panic attacks (PAs) call for new epidemiological data on PD and PAs and its subtypes in the general population. Objective To present representative data about the cross-national epidemiology of PD and PAs in accordance with DSM-5 definitions. Design and setting Nationally representative cross-sectional surveys using the World Health Organization Composite International Diagnostic Interview version 3.0. Participants Respondents (n = 142,949) from 25 high, middle, and lower-middle income countries across the world aged 18 years or older. Main outcome measures PD and presence of single and recurrent PAs. Results Lifetime prevalence of PAs was 13.2% (SE 0.1%). Among persons that ever had a PA, the majority had recurrent PAs (66.5%; SE 0.5%), while only 12.8% fulfilled DSM-5 criteria for PD. Recurrent PAs were associated with a subsequent onset of a variety of mental disorders (OR 2.0; 95% CI 1.8–2.2) and their course (OR 1.3; 95% CI 1.2–2.4) whereas single PAs were not (OR 1.1; 95% CI 0.9–1.3 and OR 0.7; 95% CI 0.6–0.8). Cross-national lifetime prevalence estimates were 1.7% (SE 0.0%) for PD with a median age of onset of 32 (IQR 20–47). Some 80.4% of persons with lifetime PD had a lifetime comorbid mental disorder. Conclusions We extended previous epidemiological data to a cross-national context. The presence of recurrent PAs in particular is associated with subsequent onset and course of mental disorders beyond agoraphobia and PD, and might serve as a generic risk marker for psychopathology.
Databáze:	OpenAIRE
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